Etrafon (perphenazine and amitriptyline) side effects, interactions, warning, dosage & uses, etrafon

DRUG DESCRIPTION

ETRAFON (perphenazine and amitriptyline) Tablets contain perphenazine, USP and amitriptyline hydrochloride, USP. Perphenazine is a piperazinyl phenothiazine having the chemical formula, C 21 H 26 CIN 3 OS. Amitriptyline hydrochloride is a dibenzocycloheptadiene derivative having the chemical formula, C 20 H 23 N. HCl.

ETRAFON (perphenazine and amitriptyline) Tablets are available in multiple strengths to afford dosage flexibility for optimum management. They are available as ETRAFON 2-10 Tablets, 2 mg perphenazine and 10 mg amitriptyline hydrochloride; ETRAFON (perphenazine and amitriptyline) Tablets, 2 mg perphenazine and 25 mg amitriptyline hydrochloride; ETRAFON (perphenazine and amitriptyline) - Forte Tablets, 4 mg perphenazine and 25 mg amitriptyline hydrochloride.

The inactive ingredients for ETRAFON 2-10 Tablets (2-10) include: acacia, butylparaben, calcium phosphate. calcium sulfate, carnauba wax, corn starch, D&C Yellow No. 10 Al Lake, FD&C Yellow No. 6 Al Lake, gelatin, lactose. magnesium stearate, potato starch, sugar, and white wax. May also contain talc.

The inactive ingredients for ETRAFON (perphenazine and amitriptyline) - Forte Tablets (4-25) include: acacia, butylparaben, calcium phosphate, calcium sulfate, carnauba wax, corn starch, FD&C Red No. 40 Al Lake, FD&C Yellow No. 6 Al Lake, gelatin, lactose, magnesium stearate, potato starch, sugar, and white wax. May also contain talc.

What are the precautions when taking perphenazine and amitriptyline (Etrafon)?

See also Warning section.

Before taking amitriptyline with perphenazine, tell your doctor or pharmacist if you are allergic to it; or to other tricyclic antidepressants (such as nortriptyline); or to other phenothiazines (such as chlorpromazine, fluphenazine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: bleeding problems, decreased bone marrow function, breathing problems (such as asthma, emphysema), liver problems, low blood pressure, recent heart attack, breast cancer, problems urinating (such as due to enlarged prostate), overactive thyroid.

Last reviewed on RxList: 12/8/2004 This monograph has been modified to include the generic and brand name in many instances.

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Description

Cozaar (generic name: losartan potassium; brand names include: Cosart / Los-Pot) belongs to a new group of medicines, called angiotensin II receptor antagonists.

Cozaar is the only medicine in its class proven to lower the chance of stroke.

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In type 2 diabetic patients with protein in the urine, Cozaar has been shown to reduce the need for dialysis or kidney transplantation.

Cozaar is not addictive.

Recommendations

Follow the directions for using this medicine provided by your doctor. Take Cozaar exactly as directed.

Cozaar is generally taken once daily.

Take Cozaar at about the same time each day. Taking your tablet(s) at the same time each day will have the best effect. It will also help you remember when to take the tablets.

Swallow Cozaar with a glass of water or other liquid. It does not matter whether you take Cozaar before or after food.

Continue taking Cozaar for as long as your doctor prescribes.

If you miss a dose of Cozaar, take it as soon as you remember. If it is close to your next dose, do not take the missed dose. Just take the next dose at your regular time.

Keep Cozaar at room temperature. Protect from light.

Precautions

Before taking Cozaar, tell your doctor if:

you are allergic to any medicines; you have kidney or liver disease; you are pregnant or breast-feeding.

Ingredients

Active ingredient: losartan potassium.

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Diflucan - anti fungal, azol-flucon

Product Description Common use Diflucan is an anti-fungal antibiotic which is used to treat fungal infections called candidiasis. This medication is prescribed for the treatment of such type of infections as vaginal, throat and fungal infections, infections of the urinary tract, peritonitis, and pneumonia. Diflucan works by killing sensitive fungi by interfering with the formation of the fungal cell membrane.

Dosage and direction Take it orally once a day, with or without food using the measuring spoon. Take it at the same time each day with a full glass of water if you want to get the best result. Diflucan make you feel better after 24 hours. However, your symptoms will go away completely just after few days. If there is no change in your health after a few days consult your doctor immediately. The dosage for adults may vary from type of infection: 1) Genital thrush - 150mg as a single dose 2) Mucosal thrush - dose depends on where the infection is located 50mg once daily during month. 3)Fungal skin infections - 50mg once daily for 2-4 weeks ; 4) Internal fungal infections 400mg on the first day then 200-400mg once daily for 6-8 weeks or longer if needed. 5) To stop you from getting fungal infections - 50-400mg once daily while you have risk to get an infection; 6) To stop infection caused by Cryptococcus from coming back - 100-200mg once daily indefinitely The dosage for children 4 weeks to 15 years old may also vary from type of infection: 1) mucosal infections - 3mg/kg once daily; 2)internal fungal infections - 6-12mg/kg once daily; 3)prevention of fungal infections - 3-12mg/kg once daily while at risk of getting an infection. For children 2-4 weeks old it is same dose as above but given once every 2 days. A maximum dose of 12mg/kg every 2 days. For children less than 2 weeks old it is same dose as above but given once every 3 days. Do not give more then 12mg/kg every 3 days. Note: this instruction presented here is just for review. It's very necessary to consult your doctor before using. It will help you to get best results.

For vaginal yeast infections, doctors usually prescribe a single dose of Diflucan. If the yeast infection does not improve after 5 days, contact your doctor as soon as possible. Be careful with this medication if your medical history include liver disease or kidney disease. Although uncommon, this drug may make you dizzy, so be more attentive while you are driving or using machinery. Limit alcohol intake. Diflucan should not be used during pregnancy, lactation or if you plan to become pregnant without a doctor's advice. Do not use before breast-feeding without a doctor's advice.

Contraindications Diflucan is not allowed to people who have hypersensitivity to Fluconazole or other anti fungal azole preparations, eg clotrimazole, ketoconazole, itraconazole and other. Also Diflucan contraindicated in: Kidney and liver disorders; Cardiovascular diseases including heart diseases(heart rate or rhythm disturbances); Low blood levels of calcium, magnesium or potassium.

Possible side effect

They may include an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Also the most possible side effects include: nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); fever, chills, body aches, flu symptoms; severe blistering, peeling, and red skin rash; easy bruising or bleeding, unusual weakness; or seizure (convulsions). Less serious include: mild nausea, vomiting, diarrhea, or upset stomach; headache; dizziness; unusual or unpleasant taste in your mouth; or skin rash or itching. If you experience one of them stop using Diflucan and tell your doctor as soon as possible. Also consult your doctor about any side effect that seems unusual.

Drug interaction Diflucan interact with such medication as: a blood thinner such as warfarin (Coumadin) cyclosporine (Gengraf, Sandimmune, Neoral); an oral diabetes medicine such as glipizide (Glucotrol), glyburide (Diabeta, Micronase, Glynase), tolbutamide (Orinase), tolazamide (Tolinase), chlorpropamide (Diabinese), and others; rifabutin (Mycobutin) or rifampin (Rifadin, Rifater, Rifamate, Rimactane); a sedative such as diazepam (Valium), lorazepam (Ativan), alprazolam (Xanax), or midazolam (Versed); seizure medication such as phenytoin (Dilantin) or valproic acid (Depakene); tacrolimus ((Prograf); theophylline (Theo-Dur, Theolair, Theochron, Elixophyllin, Slo-Phyllin, others). Also note that interaction between two medications does not always mean that you must stop taking one of them. Usually it affects the the effect of drugs, so consult your doctor about the way these interactions are being managed or should be managed.

Missed dose If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not take double or extra doses. Take your usual dose next day in the same time.

Overdose Symptoms of Diflucan overdose may include: confusion or unusual thoughts or behavior. If you experience one of them call your doctor immediately.

Storage Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture, kids and pets. Do not use after expiration term.

Disclaimer We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information on the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Anti Fungal - Azol-flucon (Brand name: diflucan)

Product Description Common use Diflucan is an anti-fungal antibiotic which is used to treat fungal infections called candidiasis. This medication is prescribed for the treatment of such type of infections as vaginal, throat and fungal infections, infections of the urinary tract, peritonitis, and pneumonia. Diflucan works by killing sensitive fungi by interfering with the formation of the fungal cell membrane.

Dosage and direction Take it orally once a day, with or without food using the measuring spoon. Take it at the same time each day with a full glass of water if you want to get the best result. Diflucan make you feel better after 24 hours. However, your symptoms will go away completely just after few days. If there is no change in your health after a few days consult your doctor immediately. The dosage for adults may vary from type of infection: 1) Genital thrush - 150mg as a single dose 2) Mucosal thrush - dose depends on where the infection is located 50mg once daily during month. 3)Fungal skin infections - 50mg once daily for 2-4 weeks ; 4) Internal fungal infections 400mg on the first day then 200-400mg once daily for 6-8 weeks or longer if needed. 5) To stop you from getting fungal infections - 50-400mg once daily while you have risk to get an infection; 6) To stop infection caused by Cryptococcus from coming back - 100-200mg once daily indefinitely The dosage for children 4 weeks to 15 years old may also vary from type of infection: 1) mucosal infections - 3mg/kg once daily; 2)internal fungal infections - 6-12mg/kg once daily; 3)prevention of fungal infections - 3-12mg/kg once daily while at risk of getting an infection. For children 2-4 weeks old it is same dose as above but given once every 2 days. A maximum dose of 12mg/kg every 2 days. For children less than 2 weeks old it is same dose as above but given once every 3 days. Do not give more then 12mg/kg every 3 days. Note: this instruction presented here is just for review. It's very necessary to consult your doctor before using. It will help you to get best results.

For vaginal yeast infections, doctors usually prescribe a single dose of Diflucan. If the yeast infection does not improve after 5 days, contact your doctor as soon as possible. Be careful with this medication if your medical history include liver disease or kidney disease. Although uncommon, this drug may make you dizzy, so be more attentive while you are driving or using machinery. Limit alcohol intake. Diflucan should not be used during pregnancy, lactation or if you plan to become pregnant without a doctor's advice. Do not use before breast-feeding without a doctor's advice.

Contraindications Diflucan is not allowed to people who have hypersensitivity to Fluconazole or other anti fungal azole preparations, eg clotrimazole, ketoconazole, itraconazole and other. Also Diflucan contraindicated in: Kidney and liver disorders; Cardiovascular diseases including heart diseases(heart rate or rhythm disturbances); Low blood levels of calcium, magnesium or potassium.

Possible side effect

They may include an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Also the most possible side effects include: nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); fever, chills, body aches, flu symptoms; severe blistering, peeling, and red skin rash; easy bruising or bleeding, unusual weakness; or seizure (convulsions). Less serious include: mild nausea, vomiting, diarrhea, or upset stomach; headache; dizziness; unusual or unpleasant taste in your mouth; or skin rash or itching. If you experience one of them stop using Diflucan and tell your doctor as soon as possible. Also consult your doctor about any side effect that seems unusual.

Drug interaction Diflucan interact with such medication as: a blood thinner such as warfarin (Coumadin) cyclosporine (Gengraf, Sandimmune, Neoral); an oral diabetes medicine such as glipizide (Glucotrol), glyburide (Diabeta, Micronase, Glynase), tolbutamide (Orinase), tolazamide (Tolinase), chlorpropamide (Diabinese), and others; rifabutin (Mycobutin) or rifampin (Rifadin, Rifater, Rifamate, Rimactane); a sedative such as diazepam (Valium), lorazepam (Ativan), alprazolam (Xanax), or midazolam (Versed); seizure medication such as phenytoin (Dilantin) or valproic acid (Depakene); tacrolimus ((Prograf); theophylline (Theo-Dur, Theolair, Theochron, Elixophyllin, Slo-Phyllin, others). Also note that interaction between two medications does not always mean that you must stop taking one of them. Usually it affects the the effect of drugs, so consult your doctor about the way these interactions are being managed or should be managed.

Missed dose If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not take double or extra doses. Take your usual dose next day in the same time.

Overdose Symptoms of Diflucan overdose may include: confusion or unusual thoughts or behavior. If you experience one of them call your doctor immediately.

Storage Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture, kids and pets. Do not use after expiration term.

Disclaimer We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information on the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Adrovance 70 mg, adrovance

ADROVANCE 70 mg/5600 IU tablets

What is ADROVANCE? ADROVANCE is a tablet containing the two active substances, alendronic acid and colecalciferol known as vitamin D .

What is alendronate? Alendronate belongs to a group of non-hormonal medicines called bisphosphonates. Alendronate prevents the loss of bone that occurs in women after they have been through the menopause, and helps to rebuild bone. It reduces the risk of spine and hip fractures.

What is vitamin D? Vitamin D is an essential nutrient, required for calcium absorption and healthy bones. The body can only absorb calcium properly from our food if it has enough vitamin D. Very few foods contain vitamin D. The main source is through exposure to summer sunlight, which makes vitamin D in our skin. As we get older our skin makes less vitamin D. Too little vitamin D may lead to bone loss and osteoporosis. Severe vitamin D deficiency may cause muscle weakness which can lead to falls and a greater risk of fractures.

What is ADROVANCE used for? Your doctor has prescribed ADROVANCE to treat your osteoporosis and because you are at risk of vitamin D insufficiency. ADROVANCE reduces the risk of spine and hip fractures in women after menopause.

ADROVANCE is a once weekly treatment.

What is osteoporosis? Osteoporosis is a thinning and weakening of the bones. It is common in women after the menopause. At the menopause, the ovaries stop producing the female hormone, oestrogen, which helps to keep a woman’s skeleton healthy. As a result, bone loss occurs and bones become weaker. The earlier a woman reaches the menopause, the greater the risk of osteoporosis.

Early on, osteoporosis usually has no symptoms. If left untreated, however, it can result in broken bones. Although these usually hurt, breaks in the bones of the spine may go unnoticed until they cause height loss. Broken bones can happen during normal, everyday activity, such as lifting, or from minor injury that would not generally break normal bone. Broken bones usually occur at the hip, spine, or wrist and can lead not only to pain but also to considerable problems like stooped posture (‘dowager’s hump’) and loss of mobility.

How can osteoporosis be treated? Osteoporosis can be treated and it is never too late to begin treatment. ADROVANCE not only prevents the loss of bone but actually helps to rebuild bone you may have lost and reduces the risk of bones breaking in the spine and hip.

As well as your treatment with ADROVANCE, your doctor may suggest you make changes to your lifestyle to help your condition, such as:

Eating a balanced diet Your doctor can advise you about your diet or whether you should take any dietary supplements.

Do not take ADROVANCE

if you are allergic (hypersensitive) to alendronate sodium trihydrate, colecalciferol or any of the other ingredients,

if you have certain problems with your gullet (oesophagus - the tube that connects your mouth, with your stomach) such as narrowing or difficulty swallowing,

if you cannot stand or sit upright for at least 30 minutes,

if your doctor has told you that you have low blood calcium.

If you think any of these apply to you, do not take the tablets. Talk to your doctor first and follow the advice given.

Take special care with ADROVANCE It is important to tell your doctor before taking ADROVANCE if:

you suffer from kidney problems,

you have any swallowing or digestive problems,

your doctor has told you that you have Barrett's oesophagus (a condition associated with changes in the cells that line the lower oesophagus),

you have been told you have low blood calcium,

you have poor dental health, gum disease, a planned dental extraction or you don’t receive routine dental care,

you have cancer,

you are undergoing chemotherapy or radiotherapy,

you are taking corticosteroids (such as prednisone or dexamethasone),

you are or have been a smoker (as this may increase the risk of dental problems).

You may be advised to have a dental check-up before starting treatment with ADROVANCE.

It is important to maintain good oral hygiene when being treated with ADROVANCE. You should have routine dental check-ups throughout your treatment and you should contact your doctor or dentist if you experience any problems with your mouth or teeth such as loose teeth, pain or swelling.

Irritation, inflammation or ulceration of the gullet (oesophagus – the tube that connects your mouth with your stomach) often with symptoms of chest pain, heartburn, or difficulty or pain upon swallowing may occur, especially if patients do not drink a full glass of water and/or if they lie down less than 30 minutes after taking ADROVANCE. These side effects may worsen if patients continue to take ADROVANCE after developing these symptoms.

Use in children ADROVANCE should not be given to children less than 18 years of age.

Taking other medicines Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.

It is likely that calcium supplements, antacids, and some oral medicines will interfere with the absorption of ADROVANCE if taken at the same time. Therefore, it is important that you follow the advice given in section 3. HOW TO TAKE ADROVANCE and wait at least 30 minutes before taking any other oral medicines or supplements.

It is likely that certain medicines or food additives may prevent the vitamin D in ADROVANCE from getting into your body, including artificial fat substitutes, mineral oils, orlistat and the cholesterol-lowering medicines, cholestyramine and colestipol. Medicines for fits (seizures) may decrease the effectiveness of vitamin D.

Taking ADROVANCE with food and drink It is likely that food and beverages (including mineral water) will make ADROVANCE less effective if taken at the same time. Therefore, it is important that you follow the advice given in section 3. HOW TO TAKE ADROVANCE.

Pregnancy and breast-feeding ADROVANCE is only intended for use in postmenopausal women. You should not take ADROVANCE if you are or think you may be pregnant, or if you are breast-feeding.

Driving and using machines There have been side effects (for example blurred vision, dizziness and severe bone, muscle or joint pain) reported with ADROVANCE that may affect your ability to drive or operate machinery. (See POSSIBLE SIDE EFFECTS.) If you experience any of these side effects you should not drive until you feel better.

Important information about some of the ingredients of ADROVANCE ADROVANCE contains lactose and sucrose. If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.

Always take ADROVANCE exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure.

Take one ADROVANCE tablet once a week.

Follow these instructions carefully to make sure you will benefit from ADROVANCE.

It is very important to follow instructions 2), 3), 4) and 5) to help the ADROVANCE tablet reach your stomach quickly and help reduce the chance of irritating your gullet (oesophagus - the tube that connects your mouth with your stomach).

Do not crush or chew the tablet or allow it to dissolve in your mouth.

If you take more ADROVANCE than you should If you take too many tablets by mistake, drink a full glass of milk and contact your doctor immediately. Do not make yourself vomit, and do not lie down.

If you forget to take ADROVANCE If you miss a dose, just take one tablet on the morning after you remember. Do not take two tablets on the same day. Return to taking one tablet once a week, as originally scheduled on your chosen day.

If you stop taking ADROVANCE It is important that you continue taking ADROVANCE for as long as your doctor prescribes the medicine. ADROVANCE can treat your osteoporosis only if you continue to take the tablets.

If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

Like all medicines, ADROVANCE can cause side effects, although not everybody gets them.

The frequency of possible side effects listed below is defined using the following convention: very common (affects more than 1 user in 10) common (affects 1 to 10 users in 100) uncommon (affects 1 to 10 users in 1,000) rare (affects 1 to 10 users in 10,000) very rare (affects less than 1 user in 10,000)

bone, muscle and/or joint pain which is sometimes severe.

heartburn; difficulty swallowing; pain upon swallowing; ulceration of the gullet (oesophagus - the tube that connects your mouth with your stomach) which can cause chest pain, heartburn or difficulty or pain upon swallowing,

joint swelling,

abdominal pain; uncomfortable feeling in the stomach or belching after eating; constipation; full or bloated feeling in the stomach; diarrhoea; flatulence,

hair loss; itching,

headache; dizziness,

tiredness; swelling in the hands or legs.

nausea; vomiting,

irritation or inflammation of the gullet (oesophagus – the tube that connects your mouth with your stomach) or stomach,

black or tar-like stools,

blurred vision; pain or redness in the eye,

rash; redness of the skin,

transient flu-like symptoms, such as aching muscles, generally feeling unwell and sometimes with fever usually at the start of treatment,

taste disturbance.

allergic reactions such as hives; swelling of the face, lips, tongue and/or throat, possibly causing difficulty breathing or swallowing,

symptoms of low blood calcium levels including muscle cramps or spasms and/or tingling sensation in the fingers or around the mouth,

stomach or peptic ulcers (sometimes severe or with bleeding),

narrowing of the gullet (oesophagus – the tube that connects your mouth with your stomach),

rash made worse by sunlight; severe skin reactions,

pain in the mouth, and/or jaw, swelling or sores inside the mouth, numbness or a feeling of heaviness in the jaw, or loosening of a tooth. These could be signs of bone damage in the jaw (osteonecrosis) generally associated with delayed healing and infection, often following tooth extraction. Contact your doctor and dentist if you experience such symptoms,

fracture of the thigh bone in patients on long-term treatment with ADROVANCE. Thigh pain, weakness or discomfort may be an early indication of a possible fracture of the thigh bone,

mouth ulcers when the tablets have been chewed or sucked.

If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.

It will help if you make a note of what you experienced, when it started and how long it lasted.

Keep out of the reach and sight of children.

Do not use ADROVANCE after the expiry date which is stated on the carton and the blister after EXP. The expiry date refers to the last day of that month.

Store in the original blister in order to protect from moisture and light.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

Cephalexin medlineplus drug information, cephalex

Cephalexin

Cephalexin is used to treat certain infections caused by bacteria such as pneumonia and other respiratory tract infections; and infections of the bone, skin, ears. genital, and urinary tract. Cephalexin is in a class of medications called cephalosporin antibiotics. It works by killing bacteria.

Antibiotics such as cephalexin will not work for colds, flu, or other viral infections. Using antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.

How should this medicine be used?

Cephalexin comes as a capsule, tablet, and suspension (liquid) to take by mouth. It is usually taken with or without food every 6 or 12 hours for 7 to 14 days, depending on the condition being treated. Take cephalexin at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take cephalexin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Shake the liquid well before each use to mix the medication evenly.

You should begin to feel better during the first few days of treatment with cephalexin. If your symptoms do not improve or get worse, call your doctor.

Continue to take cephalexin until you finish the prescription even if you feel better. If you stop taking cephalexin too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.

Other uses for this medicine

Cephalexin is also sometimes used for certain penicillin allergic patients who have a heart condition and are having a dental or upper respiratory tract (nose, mouth, throat, voice box) procedure, in order to prevent them from developing a heart valve infection.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before taking cephalexin,

tell your doctor and pharmacist if you are allergic to cephalexin; other cephalosporin antibiotic such as cefaclor, cefadroxil cefazolin (Ancef, Kefzol), cefdinir, cefditoren (Spectracef), cefepime (Maxipime), cefixime (Suprax), cefotaxime (Claforan), cefotetan, cefoxitin (Mefoxin), cefpodoxime, cefprozil, ceftaroline (Teflaro), ceftazidime (Fortaz, Tazicef, in Avycaz), ceftibuten (Cedax), ceftriaxone (Rocephin), and cefuroxime (Zinacef); penicillin antibiotics; or any other medications. Also tell your doctor if you are allergic to any of the ingredients in cephalexin capsules, tablets, or suspension. Ask your pharmacist for a list of the ingredients.

tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven); metformin (Fortamet, Glucophage, Glumetza, Riomet, in Glucovance, Invokamet, others); and probenecid (Probalan). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

tell your doctor if you have or have ever had any kind of allergies, gastrointestinal disease (GI; affecting the stomach or intestines), especially colitis (condition that causes swelling in the lining of the colon [large intestine]), or kidney or liver disease.

tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking cephalexin, call your doctor.

What special dietary instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Cephalexin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

nausea

diarrhea

vomiting

heartburn

stomach pain

rectal or genital itching

dizziness

extreme tiredness

agitation

confusion

headache

joint pain

Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately or get emergency medical treatment:

watery or bloody stools, stomach cramps, or fever during treatment or for up to two or more months after stopping treatment

rash

itching

hives

swelling of the face, throat, tongue, lips, and eyes

difficulty breathing or swallowing

wheezing

a return of fever, sore throat, chills, or other signs of infection

hallucinations (seeing things or hearing voices that do not exist)

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www. fda. gov/Safety/MedWatch ) or by phone (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store the capsules and tablets at room temperature and away from excess heat and moisture (not in the bathroom). Keep liquid medicine in the refrigerator, tightly closed, and dispose of any unused medication after 14 days.

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo. gl/c4Rm4p ) for more information if you do not have access to a take-back program.

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Symptoms of overdose may include:

nausea

vomiting

diarrhea

pink, red, or dark brown urine

stomach pain

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Bactrim (Groseptol)

Bactrim is used for treating infections caused by certain bacteria. Bactrim is an antibiotic combination containing a sulfonamide antibiotic. It works by killing sensitive bacteria.

Use Bactrim as directed by your doctor.

Take Bactrim by mouth with or without food.

Bactrim works best if it is taken at the same time each day.

Take Bactrim with a full glass of water (8 oz/240 mL). Drinking extra fluids while you are taking Bactrim is recommended. Check with your doctor for instructions.

To clear up your infection completely, take Bactrim for the full course of treatment. Keep taking it even if you feel better in a few days.

If you miss a dose of Bactrim, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Bactrim.

Store Bactrim at room temperature, between 59 and 77 degrees F (15 and 25 degrees C). Store away from heat, moisture, and light. Keep in a tight, light-resistant container. Do not store in the bathroom. Keep Bactrim out of the reach of children and away from pets.

Active Ingredients: Sulfamethoxazole and trimethoprim.

Do NOT use Bactrim if:

you are allergic to any ingredient in Bactrim or to similar medicines

you had a severe allergic reaction to any other sulfonamide (sulfa) medicine (eg, glipizide, hydrochlorothiazide)

you are taking dofetilide

you have anemia caused by low levels of folate in the blood or urinary blockage

you are in week 38 of pregnancy or later (full-term) or you are breast-feeding

the patient is a child younger than 2 months old

you will be receiving a live oral typhoid vaccine.

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Bactrim. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding

if you are taking any prescription (especially seizure medications) or nonprescription medicine, herbal preparation, or dietary supplement

if you have allergies to medicines, foods, or other substances

if you have liver or kidney problems, blood problems (eg, anemia, porphyria), asthma, or HIV infection

if you have severe allergies, glucose-6-phosphate dehydrogenase deficiency, or an enzyme deficiency

if you are at risk for low levels of folate in the blood (eg, you have alcoholism, you are elderly, you do not absorb nutrients from food properly, you are in a poor nutritional state, you are taking medicine for seizures).

Some medicines may interact with Bactrim. Tell your health care provider if you are taking any other medicines, especially any of the following:

Leucovorin because it may decrease Bactrim's effectiveness

Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril) or diuretics (eg, hydrochlorothiazide) because they may increase the risk of Bactrim's side effects

Anticoagulants (eg, warfarin) because the risk of bleeding may be increased

Dofetilide because the risk of severe heart problems may be increased

Digoxin, methotrexate, phenytoin, sulfones (eg, dapsone), or sulfonylureas (eg, glipizide) because the risk of their side effects may be increased by Bactrim

BCG vaccine or oral typhoid vaccine because their effectiveness may be decreased by Bactrim

Cyclosporine because its effectiveness may be decreased and the risk of liver side effects may be increased.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Bactrim may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

Bactrim may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Bactrim. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.

Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.

Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur during treatment or within several months after treatment with Bactrim. Do not treat diarrhea without first checking with your doctor.

Be sure to use Bactrim for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.

Bactrim only works against bacteria; it does not treat viral infections (eg, the common cold).

Long-term or repeated use of Bactrim may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.

Diabetes patients - Bactrim may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.

Bactrim may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Bactrim.

Lab tests, including complete blood cell counts and kidney function, may be performed while you use Bactrim. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

Use Bactrim with caution in the elderly; they may be more sensitive to its effects, especially severe skin reactions, bone marrow suppression, or high blood potassium levels.

Bactrim should not be used in children younger 2 months; safety and effectiveness in these children have not been confirmed.

Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Bactrim while you are pregnant. Do not use Bactrim if you are in week 38 of pregnancy or later (full-term). Bactrim is found in breast milk. Do not breastfeed while taking Bactrim.

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Appetite loss; diarrhea; nausea; vomiting.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); blistered, peeling, red, or swollen skin; bloody or black, tarry stools; chest pain; chills, fever, or sore throat; confusion; dark urine; decreased urination; depression; hallucinations; irregular heartbeat; joint or muscle pain; mental or mood changes; painful or stiff neck; purple patches under the skin; seizures; severe diarrhea; severe or persistent cough; severe or persistent headache; severe or persistent nausea or vomiting; shortness of breath; stomach cramps/pain; unusual bruising or bleeding; unusual tiredness or weakness; unusually pale skin; vaginal irritation or discharge; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

Customers who bought this product also bought

Bactrim (Groseptol)

Bactrim is used for treating infections caused by certain bacteria. Bactrim is an antibiotic combination containing a sulfonamide antibiotic. It works by killing sensitive bacteria.

Use Bactrim as directed by your doctor.

Take Bactrim by mouth with or without food.

Bactrim works best if it is taken at the same time each day.

Take Bactrim with a full glass of water (8 oz/240 mL). Drinking extra fluids while you are taking Bactrim is recommended. Check with your doctor for instructions.

To clear up your infection completely, take Bactrim for the full course of treatment. Keep taking it even if you feel better in a few days.

If you miss a dose of Bactrim, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Bactrim.

Store Bactrim at room temperature, between 59 and 77 degrees F (15 and 25 degrees C). Store away from heat, moisture, and light. Keep in a tight, light-resistant container. Do not store in the bathroom. Keep Bactrim out of the reach of children and away from pets.

Active Ingredients: Sulfamethoxazole and trimethoprim.

Do NOT use Bactrim if:

you are allergic to any ingredient in Bactrim or to similar medicines

you had a severe allergic reaction to any other sulfonamide (sulfa) medicine (eg, glipizide, hydrochlorothiazide)

you are taking dofetilide

you have anemia caused by low levels of folate in the blood or urinary blockage

you are in week 38 of pregnancy or later (full-term) or you are breast-feeding

the patient is a child younger than 2 months old

you will be receiving a live oral typhoid vaccine.

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Bactrim. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding

if you are taking any prescription (especially seizure medications) or nonprescription medicine, herbal preparation, or dietary supplement

if you have allergies to medicines, foods, or other substances

if you have liver or kidney problems, blood problems (eg, anemia, porphyria), asthma, or HIV infection

if you have severe allergies, glucose-6-phosphate dehydrogenase deficiency, or an enzyme deficiency

if you are at risk for low levels of folate in the blood (eg, you have alcoholism, you are elderly, you do not absorb nutrients from food properly, you are in a poor nutritional state, you are taking medicine for seizures).

Some medicines may interact with Bactrim. Tell your health care provider if you are taking any other medicines, especially any of the following:

Leucovorin because it may decrease Bactrim's effectiveness

Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril) or diuretics (eg, hydrochlorothiazide) because they may increase the risk of Bactrim's side effects

Anticoagulants (eg, warfarin) because the risk of bleeding may be increased

Dofetilide because the risk of severe heart problems may be increased

Digoxin, methotrexate, phenytoin, sulfones (eg, dapsone), or sulfonylureas (eg, glipizide) because the risk of their side effects may be increased by Bactrim

BCG vaccine or oral typhoid vaccine because their effectiveness may be decreased by Bactrim

Cyclosporine because its effectiveness may be decreased and the risk of liver side effects may be increased.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Bactrim may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

Bactrim may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Bactrim. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.

Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.

Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur during treatment or within several months after treatment with Bactrim. Do not treat diarrhea without first checking with your doctor.

Be sure to use Bactrim for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.

Bactrim only works against bacteria; it does not treat viral infections (eg, the common cold).

Long-term or repeated use of Bactrim may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.

Diabetes patients - Bactrim may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.

Bactrim may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Bactrim.

Lab tests, including complete blood cell counts and kidney function, may be performed while you use Bactrim. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

Use Bactrim with caution in the elderly; they may be more sensitive to its effects, especially severe skin reactions, bone marrow suppression, or high blood potassium levels.

Bactrim should not be used in children younger 2 months; safety and effectiveness in these children have not been confirmed.

Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Bactrim while you are pregnant. Do not use Bactrim if you are in week 38 of pregnancy or later (full-term). Bactrim is found in breast milk. Do not breastfeed while taking Bactrim.

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Appetite loss; diarrhea; nausea; vomiting.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); blistered, peeling, red, or swollen skin; bloody or black, tarry stools; chest pain; chills, fever, or sore throat; confusion; dark urine; decreased urination; depression; hallucinations; irregular heartbeat; joint or muscle pain; mental or mood changes; painful or stiff neck; purple patches under the skin; seizures; severe diarrhea; severe or persistent cough; severe or persistent headache; severe or persistent nausea or vomiting; shortness of breath; stomach cramps/pain; unusual bruising or bleeding; unusual tiredness or weakness; unusually pale skin; vaginal irritation or discharge; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

Customers who bought this product also bought

Alertrin, alertrin

Alertrin

Important Notice: The Drugs. com international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.

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Loratadine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose. Alavert is used for relieving symptoms of seasonal allergies.

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Do not crush, chew, or break the regular loratadine tablet. Swallow the pill whole. Measure liquid medicine with a special dose-measuring spoon or medicine cup, not with a regular table spoon.

Alavert is usually taken once per day. Follow your doctor's instructions.

To take Alavert orally disintegrating tablet:

Keep the tablet in its blister pack until you are ready to take the medicine. Open the package and peel back the foil from the tablet blister. Do not push a tablet through the foil or you may damage the tablet.

Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing.

Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing.

Using dry hands, remove the tablet and place it on your tongue. It will begin to dissolve right away.

Take Alavert by mouth with food.

Store at room temperature between 20 and 25 degrees C and away from moisture, light and heat. Do not store in the bathroom. Keep in a tight, light-resistant container. Keep Alavert out of the reach of children and away from pets.

You should not take Alavert if:

You are allergic to loratadine or to desloratadine (Clarinex). Ask a doctor or pharmacist if it is safe for you to take this medicine if you have:

kidney disease; Ask a doctor or pharmacist if it is safe for you to take this medicine if you have:

You should not take this medication if you are allergic to loratadine or to desloratadine (Clarinex).

FDA pregnancy category B: This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Loratadine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Loratadine disintegrating tablets (Claritin Reditab, Alavert) may contain phenylalanine. Talk to your doctor before using this form of loratadine if you have phenylketonuria (PKU). Do not give this medication to a child younger than 6 years old without the advice of a doctor.

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

fast or uneven heart rate;

feeling like you might pass out;

jaundice (yellowing of your skin or eyes);

seizures (convulsions).

Call your doctor at once if you noticed these serious side effects. Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Less serious side effects may include:

headache;

skin rash;

nervousness;

nosebleed;

feeling tired or drowsy;

eye redness, blurred vision;

stomach pain, diarrhea;

dry mouth, sore throat hoarseness.

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Other names used:

The commercial name of the medication may differ from the brand one. Sildenafil super active manufactured by Dharam Distributors is available under commercial name Sildigra.

How does Sildenafil super active work and what pharmaceutical group does it belong to?

Sildenafil is a reversible PDE-5 inhibitor. The preparation works by improving the quality of the erection as well as helping patients who cannot achieve an erection to have a normal sexual intercourse. The difference between Sildenafil and Sildenafil super active consists in the form of the preparation and the

Which conditions are treated with Sildenafil?

The preparation is normally used in treatment of erectile dysfunction.

What should a patient know before using Sildenafil super active?

Consult your doctor before starting the use of Sildenafil in:

Hypersensitivity to any components of the preparation

Cardiovascular disorders

Liver or kidney disorders

Haemopoietic disorders

Gastrointestinal disorders

Retinitis pigmentosa

Peyronie's disease

Which adverse effects may manifest when using the medication?

The side effects of Sildenafil super active include:

Back pain

Face flushing

Nasal congestion

Memory problems

Headache

GI disturbance

Sildenafil should be discontinued in case of the following side effects appearance:

vision impairment

sudden hearing loss or hearing impairment

chest pain, fainting

irregular heartbeat

swelling of the extremities

vision changes;

light-headedness

Along lasting erection over 4 hours

It is not necessary that the side effects will manifest in an individual but the possibility still exist. For more information please consult your health care provider.

Which groups of drugs or specific preparations may interact with medicine?

The drug is affected by the following:

Nitrates

Antidepressants

NSAID's

Tuberculosis treatment

Antibiotics

Anti-fungals

Hormones and hormonal inhibitors

HIV/AIDS treatment preparations

Tell your doctor about all the herbal preparations as well as prescription drugs that you are currently taking even if they are not on the list.

Important information for the patient: Sildenafil super active is supplied for individual use. Do not use it to treat other conditions not listed in the leaflet. Keep the product out of children reach. Do not reuse any disposable materials if supplied with the preparation.

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Herbal ED Treatment

Herbal treatment for impotence includes several herbs and herbal supplements. If a man prefers the natural way of treatment, the herbal supplements are not the option. The supplements are not recommended by FDA in the cure for the sexual disease. Besides, FDA warns that very often these products do not contain the real information about the chemicals that comprise the composition of these herbals. Usually, the manufacturers of these botanicals do not mention the chemicals on the package that can influence the health of a man and even interact with certain drugs and food products. The herbal supplements are not FDA approved, so their efficiency in the cure for impotence is doubtful. The same is about the penile creams that have not been tested according to the demands of the organization.

However, impotence can be treated by the herbs and certain elements found in the food products. The intake of the natural plants and their roots can work wonders for impotent men. In some cases, such treatment can prevent ED and even stimulate an erection, if this method is regularly used. The first effective amino acid is called L-arginine. This acid can be found in such products as poultry, fish, red meat and dairy products. The scientists have studied this method for ED cure and they approved its safety and possible positive influence on the erectile function. As it is a vasodilator, L-arginine widens the blood vessels – the principle of work that reminds the PDE 5 inhibitors in the formula of ED drugs.

Another safe ED cure is the intake of dehydroepiandrosterone. A male body produces this hormone. However, one can take it from the combination of soy and wild yam. The studies of this method have shown that it is safe for the male health and it can be effective in ED cure if this sexual disease is not caused by diabetes and certain nerve disorders. Unfortunately, this method can cause hair loss and upset of stomach. Some drug may interact with this hormone in a negative way. The treatment therapy should last several months to have some effect. The most effective herbal treatment is the intake of the red ginseng.

Viagra Super Active

The pharmaceutical company Dr. Johns created the gel form of Viagra tablets. A gel capsule form dissolves faster than the simple tablet. Besides, it can stay in the blood flow up to 6 hours. Sildenafil gel capsules provide better and faster dissolution of the PDE 5 inhibitor. This medicine needs to be prescribed by a medical specialist qualified in the field of ED treatment. You may have to test your blood, hormones, the state of the sexual function and certain health conditions to be sure that this medicine is safe for the intake. Viagra Super Active is used to cure the symptoms of ED and its severe stage. You can buy Intagra online. This medicine includes the same PDE 5 inhbitor.

How to Take Viagra Gel Capsules?

With this ED medicine, the intake of the water glass is optional. The gel capsules with Viagra should be used in 15-20 minutes before intimacy. This medicine is capable of enhancing the erectile stimulation for 6 hours. Ask your urologist to prescribe the dosage. Read carefully the information on the prescription label. The dose of Viagra Super Active per one day is 100 mg of Sildenafil. The dosage may be decreased. But, it is not allowed to increase the daily dose of Sildenafil.

What to Avoid with Sildenafil Gel Capsules?

If you regularly take such drugs as nitrates, fungal pills, HIV medicines, blood tablets, other ED medicines with Sildenafil and grapefruit juice, avoid the intake of Viagra Super Active capsules. Some vitamins and herbal supplements can also influence the effect of this medicine. The intake of a fatty meal and the alcoholic drinks is also not allowed. Another ED drug produced in a gel capsule is Cialis Super Active 20 mg manufactured by Dr. Johns.

Contraindicated Diseases

Viagra Super Active is the ED medicine that should not be used by men with the following health conditions: liver failure, stroke, cardiac diseases, priapism, sickle cell anemia, leukemia, high blood pressure, penis deformations, hypersensitive reaction to Sildenafil and peyronie’s disease. Try Caverta pills if you prefer the simple ED tablets.

Viagra Super Active Side Effects

This drug can lead to dizziness, diarrhea, a mild headache, blurred vision, seizures, muscle pain, redness of the face, swelling and dyspepsia.

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Daklinza

Active Substance: daclatasvir dihydrochloride Common Name: daclatasvir ATC Code: J05AX14 Marketing Authorisation Holder: Bristol-Myers Squibb Pharma EEIG Active Substance: daclatasvir dihydrochloride Status: Authorised Authorisation Date: 2014-08-22 Therapeutic Area: Hepatitis C, Chronic Pharmacotherapeutic Group: Antivirals for systemic use

Therapeutic Indication

Daklinza is indicated in combination with other medicinal products for the treatment of chronic hepatitis C virus (HCV) infection in adults (see sections 4.2, 4.4 and 5.1).

For HCV genotype specific activity, see sections 4.4 and 5.1.

What is Daklinza and what is it used for?

Daklinza is an antiviral medicine used in combination with other medicines to treat chronic (long-term) hepatitis C (an infectious disease of the liver, caused by the hepatitis C virus) in adults.

It contains the active substance daclatasvir.

How is Daklinza used?

Daklinza can only be obtained with a prescription and treatment should be started and monitored by a doctor experienced in the management of patients with chronic hepatitis C.

Daklinza is available as 30, 60, and 90 mg tablets. The usual dose is 60 mg once a day. The dose may have to be raised or lowered if the patient is taking other medicines that decrease or increase Daklinza’s effects. Daklinza must be used in combination with other medicines for chronic hepatitis C, such as sofosbuvir, peginterferon alfa and ribavirin.

The combination of medicines to use and the duration of treatment will depend on the genotype (genetic make-up) of hepatitis C virus the patient is infected with and the nature of the patient’s liver problem, for example liver cirrhosis (scarring) or the liver not working well enough. For further information, see the package leaflet.

How does Daklinza work?

The active substance in Daklinza, daclatasvir, blocks the action of a protein in the hepatitis C virus called ‘NS5A’, which is essential for the virus to multiply. By blocking this protein, the medicine stops the hepatitis C virus from multiplying. There are several genotypes of the hepatitis C virus and Daklinza has been shown to be effective against genotypes 1 to 4.

What benefits of Daklinza have been shown in studies?

Daklinza used in combination with sofosbuvir (with or without ribavirin) was effective at clearing the hepatitis C virus from the blood in a main study involving 211 adults. The patients in the study were infected with genotypes 1, 2 or 3 and all received treatment for 12 or 24 weeks. Most patients had not previously been treated for hepatitis C, though some had genotype 1 infection that was resistant to standard medicines (consisting of either telaprevir or boceprevir – the so-called NS3/4A inhibitors - in combination with peginterferon alfa and ribavirin).

Around 99% of patients with genotype 1 infection (125 out of 126), 96% of patients with genotype 2 infection (25 out of 26) and 89% of patients with genotype 3 infection (16 out of 18) did not show any sign of the virus in their blood 12 weeks after the end of their planned treatment.

Additional studies involving patients with genotypes 4 indicate that Daklinza is also as effective against genotype 4 as it is against genotype 1.

What are the risks associated with Daklinza?

The most common side effects reported with Daklinza in combination with sofosbuvir with or without ribavirin are fatigue (tiredness), nausea (feeling sick) and headache. For the full list of all side effects reported with Daklinza, see the package leaflet.

Daklinza must not be used together with certain medicines that may reduce the effects of Daklinza. For more information on the medicines that should not be taken with Daklinza, see the package leaflet.

Why is Daklinza approved?

The Agency’s Committee for Medicinal Products for Human Use (CHMP) noted that Daklinza used in combination with other medicines was shown to be effective against hepatitis C virus, including in patients with genotype 1 resistant to previous treatment. Almost all the patients in the main study had the virus cleared from their blood.

Regarding its safety, Daklinza was well tolerated and the side effects were similar to those experienced by patients taking placebo.

The Committee therefore concluded that the benefits of Daklinza outweigh its risks and recommended that it be approved for use in the EU.

What measures are being taken to ensure the safe and effective use of Daklinza?

Recommendations and precautions to be followed by healthcare professionals and patients for the safe and effective use of Daklinza have been included in the summary of product characteristics and the package leaflet.

Further information can be found in the summary of the risk management plan.

Other information about Daklinza

The European Commission granted a marketing authorisation valid throughout the European Union for Daklinza on 22 August 2014.

For more information about treatment with Daklinza, read the package leaflet (also part of the EPAR) or contact your doctor or pharmacist.

Source: European Medicines Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.

Aciclovir - anti viral, aciclovax

Common use Aciclovir is an antiviral drug, it is a synthetic ingredient with a similar molecular structure to purine nucleoside. Aciclovir is used to treat viral infections such as cold sores, to stop the growth of Herpes simplex virus, Varicella zoster virus (caused by chickenpox and shingles), Epstein Barr Virus (caused by glandular fever), and to a lesser extent Cytomegalovirus (CMV). It is also useful in preventing genital herpes and in preventing viral infections occurring in those with a lowered immune system. This medication may also help reduce the time when pain remains after the sores heal. In addition, in people with a weakened immune system, Aciclovir can decrease the risk of the virus spreading to other parts of the body and causing serious infections.

Dosage and direction

Take this medication by mouth with or without food, usually 2 to 5 times a day as directed by your doctor. Take this medicine by mouth with a glass of water. Take your medicine at regular intervals. Do not take your medicine more often than directed. Take all of your medicine as directed even if you think your are better. If you are using the liquid form of this medication, shake the bottle well before each dose. Carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose. Dosage is based on your medical condition and response to treatment. In children, dosage is also based on weight.

You should talk with your healthcare provider prior to taking Aciclovir if you have kidney disease, including kidney failure (renal failure), any allergies, including allergies to food, dyes, or preservatives. Let your healthcare provider know if you are pregnant or thinking of becoming pregnant, breastfeeding. Make sure to tell your healthcare provider about all medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. The medication passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug.

Aciclovir Injection is contraindicated for patients who develop hypersensitivity to Aciclovax or valaciclovir.

Possible side effects Side effects are potentially serious and you should report to your doctor or health care professional as soon as possible. These include, but are not limited to: allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue, chest pain, confusion, hallucinations, tremor, dark urine, increased sensitivity to the sun, redness, blistering, peeling or loosening of the skin (including inside the mouth), seizures, trouble passing urine or change in the amount of urine, unusual bleeding or bruising, or pinpoint red spots on the skin, unusually weak or tired, yellowing of the eyes or skin. Side effects that usually do not require medical attention: diarrhea, fever, headache, nausea, vomiting stomach upset. In this way report to your doctor or health care professional if they continue or are bothersome.

Drug interactions There are negative interactions that can occur when Aciclovir is combined with any of the drugs listed above. Phenytoin (Fosphenytoin) and Aciclovir: it may decrease the level of phenytoin in your blood, perhaps making it less effective. Your healthcare provider may need to measure the level of phenytoin in your blood (using a blood test) and adjust your dose as necessary. Probenecid can increase the level of Aciclovir in your blood, increasing your risk of acyclovir side effects. Your healthcare provider may need to decrease your acyclovir dosage to prevent this interaction from occurring. Acyclovir can increase the level of Tenofovir in your blood, potentially increasing your risk of side effects. Your healthcare provider may need to lower your tenofovir dosage to prevent drug interactions.

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include seizure (convulsions), hallucinations, and urinating less than usual or not at all.

Store at controlled room temperature of 15°C to 25°C (59°F to 77°F). Keep this medicine out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Disclaimer We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information on the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Common use Aciclovir is an antiviral drug, it is a synthetic ingredient with a similar molecular structure to purine nucleoside. Aciclovir is used to treat viral infections such as cold sores, to stop the growth of Herpes simplex virus, Varicella zoster virus (caused by chickenpox and shingles), Epstein Barr Virus (caused by glandular fever), and to a lesser extent Cytomegalovirus (CMV). It is also useful in preventing genital herpes and in preventing viral infections occurring in those with a lowered immune system. This medication may also help reduce the time when pain remains after the sores heal. In addition, in people with a weakened immune system, Aciclovir can decrease the risk of the virus spreading to other parts of the body and causing serious infections.

Dosage and direction

Take this medication by mouth with or without food, usually 2 to 5 times a day as directed by your doctor. Take this medicine by mouth with a glass of water. Take your medicine at regular intervals. Do not take your medicine more often than directed. Take all of your medicine as directed even if you think your are better. If you are using the liquid form of this medication, shake the bottle well before each dose. Carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose. Dosage is based on your medical condition and response to treatment. In children, dosage is also based on weight.

You should talk with your healthcare provider prior to taking Aciclovir if you have kidney disease, including kidney failure (renal failure), any allergies, including allergies to food, dyes, or preservatives. Let your healthcare provider know if you are pregnant or thinking of becoming pregnant, breastfeeding. Make sure to tell your healthcare provider about all medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. The medication passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug.

Aciclovir Injection is contraindicated for patients who develop hypersensitivity to aciclovir or valaciclovir.

Possible side effects Side effects are potentially serious and you should report to your doctor or health care professional as soon as possible. These include, but are not limited to: allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue, chest pain, confusion, hallucinations, tremor, dark urine, increased sensitivity to the sun, redness, blistering, peeling or loosening of the skin (including inside the mouth), seizures, trouble passing urine or change in the amount of urine, unusual bleeding or bruising, or pinpoint red spots on the skin, unusually weak or tired, yellowing of the eyes or skin. Side effects that usually do not require medical attention: diarrhea, fever, headache, nausea, vomiting stomach upset. In this way report to your doctor or health care professional if they continue or are bothersome.

Drug interactions There are negative interactions that can occur when Aciclovir is combined with any of the drugs listed above. Phenytoin (Fosphenytoin) and Aciclovir: it may decrease the level of phenytoin in your blood, perhaps making it less effective. Your healthcare provider may need to measure the level of phenytoin in your blood (using a blood test) and adjust your dose as necessary. Probenecid can increase the level of Aciclovir in your blood, increasing your risk of acyclovir side effects. Your healthcare provider may need to decrease your acyclovir dosage to prevent this interaction from occurring. Acyclovir can increase the level of Tenofovir in your blood, potentially increasing your risk of side effects. Your healthcare provider may need to lower your tenofovir dosage to prevent drug interactions.

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include seizure (convulsions), hallucinations, and urinating less than usual or not at all.

Store at controlled room temperature of 15°C to 25°C (59°F to 77°F). Keep this medicine out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Disclaimer We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information on the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Common use Aciclovir is an antiviral drug, it is a synthetic ingredient with a similar molecular structure to purine nucleoside. Aciclovir is used to treat viral infections such as cold sores, to stop the growth of Herpes simplex virus, Varicella zoster virus (caused by chickenpox and shingles), Epstein Barr Virus (caused by glandular fever), and to a lesser extent Cytomegalovirus (CMV). It is also useful in preventing genital herpes and in preventing viral infections occurring in those with a lowered immune system. This medication may also help reduce the time when pain remains after the sores heal. In addition, in people with a weakened immune system, Aciclovir can decrease the risk of the virus spreading to other parts of the body and causing serious infections.

Dosage and direction

Take this medication by mouth with or without food, usually 2 to 5 times a day as directed by your doctor. Take this medicine by mouth with a glass of water. Take your medicine at regular intervals. Do not take your medicine more often than directed. Take all of your medicine as directed even if you think your are better. If you are using the liquid form of this medication, shake the bottle well before each dose. Carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose. Dosage is based on your medical condition and response to treatment. In children, dosage is also based on weight.

You should talk with your healthcare provider prior to taking Aciclovir if you have kidney disease, including kidney failure (renal failure), any allergies, including allergies to food, dyes, or preservatives. Let your healthcare provider know if you are pregnant or thinking of becoming pregnant, breastfeeding. Make sure to tell your healthcare provider about all medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. The medication passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug.

Aciclovir Injection is contraindicated for patients who develop hypersensitivity to aciclovir or valaciclovir.

Possible side effects Side effects are potentially serious and you should report to your doctor or health care professional as soon as possible. These include, but are not limited to: allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue, chest pain, confusion, hallucinations, tremor, dark urine, increased sensitivity to the sun, redness, blistering, peeling or loosening of the skin (including inside the mouth), seizures, trouble passing urine or change in the amount of urine, unusual bleeding or bruising, or pinpoint red spots on the skin, unusually weak or tired, yellowing of the eyes or skin. Side effects that usually do not require medical attention: diarrhea, fever, headache, nausea, vomiting stomach upset. In this way report to your doctor or health care professional if they continue or are bothersome.

Drug interactions There are negative interactions that can occur when Aciclovir is combined with any of the drugs listed above. Phenytoin (Fosphenytoin) and Aciclovir: it may decrease the level of phenytoin in your blood, perhaps making it less effective. Your healthcare provider may need to measure the level of phenytoin in your blood (using a blood test) and adjust your dose as necessary. Probenecid can increase the level of Aciclovir in your blood, increasing your risk of acyclovir side effects. Your healthcare provider may need to decrease your acyclovir dosage to prevent this interaction from occurring. Acyclovir can increase the level of Tenofovir in your blood, potentially increasing your risk of side effects. Your healthcare provider may need to lower your tenofovir dosage to prevent drug interactions.

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include seizure (convulsions), hallucinations, and urinating less than usual or not at all.

Store at controlled room temperature of 15°C to 25°C (59°F to 77°F). Keep this medicine out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Disclaimer We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information on the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

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Bellissima

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If fabulous shopping and dining are on your list of must-haves, you'll absolutely cherish living at Bellissima with the Desert Ridge, High Street District, & Scottsdale 101 shopping centers nearby.

Every home we build helps showcase our commitment to providing incredibly energy-efficient homes that let you spend your money on better things than utility bills. After all, we believe in building new homes and communities the way they can, and should be, built. That's why every Monterey home in Bellissima is built standard with the following energy - and money-saving features:

-2" x 6" High Performance Wall System - CFL & LED Lighting and Fixtures - ENERGY STAR® Appliances - ENERGY STAR® Programmable Thermostat - Fresh-Air Intake - Low VOC Carpets, Paints and Finishes - Low-E2 Vinyl Windows - Merv 8 Air Filters - Optional Solar System - SEER 14 HVAC - Spray-Foam Insulation - Water-Efficient Fixtures - Weather-Sensing Irrigation

Schools HORSESHOE TRAILS ELEMENTARY

Horseshoe Trails Elementary School encourages students to think, work and expect the best from themselves and others as global citizens.

Ranked as an A+ School, our goal is to provide students with academic opportunities that are second to none. Classrooms are built with research-based best practices that include: writers' workshop, discovery learning in science, technology-driven lessons and presentations by staff and students.

We have experienced, gifted-endorsed teachers to meet the needs of our gifted students. We're also a Response to Intervention school with specialized lessons for reading, writing, math and behavior interventions.

Our Chinese program helps students develop an appreciation for different cultures by learning a world language. We also have a horse arena on campus where students can strengthen their character through equestrian activities. Other unique programs include all-day free Kindergarten, Art, Music, Health and Wellness, Love and Logic and Zoo Phonics.

SONORAN TRAILS MIDDLE SCHOOL

At Sonoran Trails Middle School, we provide a safe, nurturing environment designed to meet the unique needs of middle school students. With clearly defined academic and behavior expectations in place, we work diligently to help our students achieve excellence.

Our primary academic goal is to increase reading, writing, math and critical-thinking skills in all students. We also offer access to the latest technologies for research, communication and collaboration. And our unique World Language programs help raise global awareness and prepare our students for high school, college and career opportunities.

Students are also encouraged to take advantage of other programs such as Art, Band, Chorus, Drama, Applied Science Lab and more.

CACTUS SHADOWS HIGH SCHOOL

Cactus Shadows High School provides opportunities for each student to become a lifelong learner and develop into a productive member of a global society. We have an outstanding reputation for producing highly successful students who move on after high school to make an impact in our community, state, country and the world.

Students learn to read and communicate effectively, exhibit critical and creative thinking skills, solve problems cooperatively and individually, and master the use of computers and technology.

We also have many academic opportunities and programs of study for students with diverse backgrounds, including the International Baccalaureate program, Advance Placement, Dual Enrollment, Honors education and an Early College program in partnership with Paradise Valley Community College.

Students also have the opportunity to be involved in Art, Band, Dance, Theater, Nurses Assistant Program, Honors/AP/IB and more.

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Home, pricing and community information is subject to change, and homes to prior sale, at any time without notice or obligation. Pricing may not include lot premiums or other amounts allocable to a specific lot selection. Not an offer or solicitation to sell real property. Offers to sell real property may only be made and accepted at the sales center for individual Meritage Homes communities. Meritage Homes®, Meritage Active Adult, Monterey Homes, Legendary Communities, and Phillips Builders are all trademarks of Meritage Homes Corporation.

Energy Savings Actual savings may vary and may depend in part on occupant behavior, timing, and/or fluctuating costs of energy usage and actual climate zone conditions. All referenced energy savings, water reduction, and ultraviolet ray reduction information is based on data published by the EPA and DOE.

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COMMUNITY, PLAN NAME, PURCHASE PRICE: Home, features, and community information is subject to change, and homes to prior sale, at any time without notice or obligation. Photographs are representative and may depict or contain floor plans, square footages, elevations, options, upgrades, decorations, landscaping, pool, spa, furnishings, appliances, and other design features and amenities that are not included as part of the home and/or may not be available in all communities. Additionally, deviations and variations may exist in any constructed home, including, without limitation: (i) substitution of materials and equipment of substantially equal or better quality; (ii) minor style, lot orientation, and color changes; (iii) minor variances in square footage and in room and space dimensions, and in window, door, utility outlet, and other improvement locations; (iv) changes as may be required by any state, federal, county, or local governmental authority in order to accommodate requested selections and/or options; and (v) value engineering and field changes.

Community map depictions are not an official site plan, may not be drawn to scale, and may not reflect all easements and other matters affecting the community. Rather, it is an artist's conceptual rendering intended to give Buyer a general overview of the contemplated community. Any map depiction does not constitute a guaranty that the community will be built out or developed as shown and Meritage has not made, does not make, and specifically negates and disclaims any representations, warranties, and guarantees with respect to the map depiction, including, but not limited to, any depiction or description of any physical characteristics of the community or any improvements pertaining thereto, and any depiction or description of the real estate comprising or contemplated to comprise the community or of the units or amenities (such as pools, gazebos, hike and bike trails, exercise facilities, etc.) contemplated to be a part of the community. The party developing the community may make changes in the design and plan of the community (including, without limitation, the number of homes and/or the sizes of lots in the Community), and in any currently contemplated timing of the development of the community, and Meritage reserves the right to make any and all such changes.

Floorplans: Floorplan rendering is an artist's conceptual rendering intended to provide a general overview. It does not constitute actual plans and specifications for any home and may depict elevations, options, upgrades, features, and amenities that are not included as part of the home and/or may not be available for all lots and/or in all communities. The floorplan rendering may not be drawn to scale. Any dimensions on the floorplan rendering are approximate and actual dimensions may vary. Plans and specifications are subject to change without notice. Homes may be constructed with a floorplan that is the reverse of the floorplan rendering. Plans are copyrighted and/or otherwise subject to intellectual property rights of Meritage and/or others and cannot be reproduced or copied without Meritage's prior written consent.

Energy Savings: Actual savings may vary and may depend in part on occupant behavior, timing, and/or fluctuating costs of energy usage and actual climate zone conditions. All referenced energy savings, water reduction, and ultraviolet ray reduction information is based on data published by the EPA and DOE.

The builder licenses are as followed: AZ ROC Lic # B-166223, CGC#1516367.

*** Availability Plans, dimensions, features, specifications, materials, and availability of homes or communities are subject to change without notice or obligation.

Estimated completion dates are based on available information at the time the estimates are made and are subject to adjustment from time to time. Normal construction schedules may be affected by municipalities' processing delays and inspections, weather conditions, fires, acts of God, the availability of materials and qualified trade contractors, schedule changes, and other factors and, therefore, Meritage does not and cannot guarantee a completion date and Meritage cannot be held responsible for any estimated completion dates that may be made at any time. Further, Meritage assumes no duty to update any such estimates. Meritage's sole responsibility for completion of a home, if any, shall be as provided in the applicable purchase agreement entered into with the buyer of the home.

Picture is representative and may depict or contain, and features list above may contain, floor plan, square footage, elevation, options, upgrades, design features, decorations, furnishings, appliances, and other features and amenities that are not included as part of all homes and/or may not be available in all communities. Plans, dimensions, features, specifications, materials, and availability of homes and/or communities are subject to change without notice or obligation. See sales associate for complete details. All promotional, marketing, and advertising estimates and claims, including, without limitation, claims related to energy savings or performance, and related certifications, exclude attached product communities, all communities in Tennessee, all communities acquired in connection with Meritage’s acquisition of certain assets of Legendary Communities in the Charlotte, North Carolina and York County, South Carolina markets, and may not be applicable to homes in certain existing communities in Georgia, and Greenville and Spartanburg, South Carolina. © 2016 Meritage Homes Corporation. All rights reserved.

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Lexapro side effects in detail, lexapram

Lexapro Side Effects

Note: This page contains information about the side effects of escitalopram. Some of the dosage forms included on this document may not apply to the brand name Lexapro.

In Summary

Common side effects of Lexapro include: insomnia, headache, drowsiness, diarrhea, nausea, ejaculatory disorder, and delayed ejaculation. Other side effects include: dizziness, fatigue, constipation, dyspepsia, anorgasmia, diaphoresis, xerostomia, and decreased libido. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to escitalopram: oral solution, oral tablet

In addition to its needed effects, some unwanted effects may be caused by escitalopram (the active ingredient contained in Lexapro). In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking escitalopram:

Rare

Coma

confusion

convulsions

decreased urine output

dizziness

fast or irregular heartbeat

headache

increased thirst

muscle pain or cramps

nausea or vomiting

shortness of breath

swelling of the face, ankles, or hands

unusual tiredness or weakness

Minor Side Effects

Some of the side effects that can occur with escitalopram may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common:

Constipation

decreased interest in sexual intercourse

diarrhea

dry mouth

ejaculation delay

gas in the stomach

heartburn

inability to have or keep an erection

loss in sexual ability, desire, drive, or performance

sleepiness or unusual drowsiness

trouble sleeping

Less common:

Bloated or full feeling

burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

chills

cough

decreased appetite

excess air or gas in the stomach or intestines

fever

general feeling of discomfort or illness

increased sweating

joint pain

muscle aches and pains

not able to have an orgasm

pain in the neck or shoulders

pain or tenderness around the eyes and cheekbones

passing gas

runny nose

shivering

sneezing

sore throat

stuffy nose

tightness of the chest

tooth problems

trouble breathing

unusual dreams

unusual drowsiness, dullness, tiredness, weakness or feeling of sluggishness

yawning

For Healthcare Professionals

Applies to escitalopram: oral solution, oral tablet

General

Side effects have been reported to be generally mild and transient. They are most common during the first 2 weeks of treatment and decrease in intensity and frequency with continued treatment. They generally do not lead to treatment cessation.

The overall incidence of rates of side effects in trials with patients treated with escitalopram (the active ingredient contained in Lexapro) 10 mg per day (66%) was similar to placebo-treated patients (61%); the incidence rate in the group treated with escitalopram 20 mg per day was greater (86%). Common side effects that occurred in the 20 mg per day group with an incidence approximately twice that of the 10 mg group and approximately twice that of the placebo group included insomnia, diarrhea, dry mouth, somnolence, dizziness, increased sweating, constipation, fatigue, and indigestion. [Ref ]

Psychiatric

Antidepressants may have a role in inducing worsening of depression and the emergence of suicidality in certain patients during the early phases of treatment. An increased risk of suicidal thinking and behavior in children, adolescents, and young adults (aged 18 to 24 years) with major depressive disorder (MDD) and other psychiatric disorders has been reported with short-term use of antidepressant drugs.

Adult and pediatric patients receiving antidepressants for MDD, as well as for psychiatric and nonpsychiatric indications, have reported symptoms that may be precursors to emerging suicidality, including anxiety, agitation, panic attacks, insomnia, irritability, hostility, aggressiveness, impulsivity, akathisia, hypomania, and mania. Causality has not been established. [Ref ]

Very common (10% or more): Insomnia Common (1% to 10%): Abnormal dreams, agitation, anxiety, nervousness, restlessness Uncommon (0.1% to 1%): Abnormal thinking, aggravated depression, aggressive reaction, aggravated restlessness, alcohol problem, apathy, bruxism, confusion, confusional state, depersonalization, depression, emotional lability, excitability, feeling unreal, forgetfulness, hallucination, hypomania, irritability, jitteriness, obsessive-compulsive disorder, panic reaction, paroniria, sleep disorder, suicide attempt, tics Frequency not reported: Mania, suicidal ideation Postmarketing reports: Acute psychosis, anger, delirium, delusion, disorientation, non-accidental overdose, mood swings, nightmare, psychotic disorder, withdrawal syndrome [Ref ]

Nervous system

Convulsions (including grand mal convulsions) have been reported with racemic citalopram.

Potentially life-threatening serotonin syndrome has been reported with SSRIs and SNRIs as monotherapy, but particularly with concomitant use of other serotonergic drugs and drugs that impair the metabolism of serotonin. Serotonin syndrome has been reported with racemic citalopram.

At least one case of escitalopram-induced paroxysmal dystonia has been reported in the literature. A 44-year-old woman developed paroxysmal cervical-cranial dystonia after receiving several days of treatment with escitalopram (the active ingredient contained in Lexapro) The paroxysmal movement disorders were characterized by cervical and oral contracture with sustained and painful laterocollis and twisting tongue movements. The episodes occurred several times a day lasting for several minutes and would resolve spontaneously. The day after escitalopram was discontinued, the paroxysmal symptoms resolved without recurrence. [Ref ]

Very common (10% or more): Headache, somnolence Common (1% to 10%): Dizziness, paraesthesia, tremor Uncommon (0.1% to 1%): Amnesia, ataxia, carpal tunnel syndrome, cerebrovascular disorder, concentration impairment, dysesthesia, disequilibrium, dysgeusia, dystonia, hyperkinesia, hyperreflexia, hypertonia, hypoesthesia, lethargy, lightheadedness, migraine, nerve root lesion, neuralgia, neuropathy, paralysis, sedation, syncope Rare (less than 0.1%): Serotonin syndrome Frequency not reported: Abnormal gait, cerebrovascular accident, choreoathetosis, convulsions, dyskinesia, extrapyramidal disorder, grand mal convulsions, myoclonus, movement disorder, psychomotor restlessness/akathisia Postmarketing reports: Dysarthria, neuroleptic malignant syndrome, nystagmus, parkinsonism, tardive dyskinesia [Ref ]

Cardiovascular

Cases of QT interval prolongation and ventricular arrhythmias reported in postmarketing experience were predominantly in females, with hypokalemia, or with pre-existing QT interval prolongation or other cardiac diseases.

Postural hypotension has been reported with other SSRIs. [Ref ]

Common (1% to 10%): Palpitation Uncommon (0.1% to 1%): Abnormal ECG, aggravated hypertension, angina pectoris, bradycardia, chest tightness, chest pain, flushing, hot flush, hypertension, hypotension, myocardial infarction, myocardial ischemia, myocarditis, edema, edema of extremities, peripheral edema, peripheral ischemia, tachycardia, varicose vein, vein disorder, vein distended Frequency not reported: Orthostatic hypotension Postmarketing reports: Atrial fibrillation, cardiac failure, prolonged QT, deep vein thrombosis, hypertensive crisis, phlebitis, thrombosis, torsades de pointes, ventricular arrhythmia, ventricular tachycardia [Ref ]

Gastrointestinal

Very common (10% or more): Nausea Common (1% to 10%): Abdominal pain, constipation, diarrhea, dry mouth, dyspepsia, flatulence, indigestion, toothache, vomiting Uncommon (0.1% to 1%): Abdominal cramp, abdominal discomfort, belching, bloating, change in bowel habit, colitis, enteritis, epigastric discomfort, gastritis, gastrointestinal bleeding, gastrointestinal hemorrhage (including rectal hemorrhage) gastroesophageal reflux, hemorrhoids, heartburn, increased stool frequency, irritable bowel syndrome, melena, periodontal destruction, tooth disorder, ulcerative colitis, ulcerative stomatitis Frequency not reported: Gastroenteritis Postmarketing reports: Dysphagia, pancreatitis, stomatitis [Ref ]

Metabolic

Common (1% to 10%): Decreased appetite, increased appetite, weight increased Uncommon (0.1% to 1%): Abnormal glucose tolerance, carbohydrate craving, diabetes mellitus, gout, hypercholesterolemia, hyperglycemia, hyperlipemia, thirst, weight decreased Frequency not reported: Anorexia, hyponatremia Postmarketing reports: Hypoglycemia, hypokalemia [Ref ]

Numerous cases of hyponatremia have been reported following treatment with an SSRI. Risk factors for the development of SSRI - associated hyponatremia including advanced age, female gender, concomitant use of diuretics, low body weight, and lower baseline serum sodium levels have been identified. Hyponatremia tends to develop within the first few weeks of treatment (range 3 to 120 days) and typically resolves within 2 weeks (range 48 hours to 6 weeks) after therapy has been discontinued with some patients requiring treatment. The proposed mechanism for the development of hyponatremia involves SIADH via release of antidiuretic hormone.

A 62-year-old woman developed hyponatremia approximately 3- weeks after initiating treatment with escitalopram. Following discontinuation of the drug and administration of intravenous normal saline solution, the patient's serum sodium and serum and urine osmolality returned to normal levels.

In a similar case, hyponatremia developed in a 75-year-old woman five days after initiating treatment with escitalopram. Following discontinuation of escitalopram serum sodium levels returned to normal values over a period of 5 days. The authors suggest that the risk of hyponatremia is highest during the initial weeks of treatment and is higher in women than in men, in patients 65 years of age or older, and in patients receiving multiple drugs that may also cause hyponatremia. [Ref ]

Other

Common (1% to 10%): Fatigue, pyrexia Uncommon (0.1% to 1%): Abscess, accidental injury, asthenia, bite, burn, deafness, earache, ear disorder, ear infection not otherwise specified, facial edema, fall, food poisoning, fractured neck of femur, hernia, inflicted injury (unintended injury), malaise, otitis externa, otosalpingitis, rigors, sting, surgical intervention, tinnitus, traumatic hematoma, vertigo Postmarketing reports: Injury not otherwise specified, spontaneous abortion [Ref ]

Genitourinary

Very common (10% or more): Ejaculation disorder Common (1% to 10%): Anorgasmia, decreased libido, ejaculation failure, impotence, menstrual disorder, vaginal bleeding Uncommon (0.1% to 1%): Amenorrhea, atrophic vaginitis, breast pain, cystitis, delayed ejaculation, dysmenorrhea, dysuria, genital infection, genital moniliasis, intermenstrual bleeding, loss of libido, menopausal symptoms, menorrhagia, menstrual cramps, metrorrhagia, micturition disorder, micturition frequency, nocturia, ovarian cyst, polyuria, postmenopausal bleeding, premenstrual tension, prostatic disorder, sexual function abnormality, unintended pregnancy, urinary incontinence, urinary retention, urinary tract infection, uterine fibroid, vaginal candidiasis, vaginal hemorrhage, vaginitis Frequency not reported: Galactorrhea, priapism [Ref ]

Urinary retention and galactorrhea have been reported with other SSRIs. The estimates of the incidence of untoward sexual experience and performance may underestimate their actual incidence, partly because patients and physicians may be reluctant to discuss this issue. [Ref ]

Dermatologic

Common (1% to 10%): Increased sweating Uncommon (0.1% to 1%): Acne, aggravated psoriasis, alopecia, cellulitis, dry skin, eczema, erythematous rash, fungal dermatitis, furunculosis, hematomas, lichenoid dermatitis, onychomycosis, pruritus, purpura, pustular rash, rash, scar, skin disorder, urticaria, verruca Frequency not reported: Angioedema, ecchymosis Postmarketing reports: Epidermal necrolysis, erythema multiforme, Stevens Johnson syndrome, toxic epidermal necrolysis [Ref ]

Angioedema has been reported with racemic citalopram. [Ref ]

Endocrine

Frequency not reported: Inappropriate antidiuretic hormone secretion (SIADH) Postmarketing reports: Hyperprolactinemia [Ref ]

Hematologic

Uncommon (0.1% to 1%): Anemia, hypochromic anemia, leucopenia Frequency not reported: Thrombocytopenia Postmarketing reports: Agranulocytosis, aplastic anemia, decreased prothrombin, hemolytic anemia, idiopathic thrombocytopenia purpura, increased INR [Ref ]

Hepatic

Uncommon (0.1% to 1%): Bilirubinemia, hepatic enzymes increased Postmarketing reports: Fulminant hepatitis, hepatic failure, hepatic necrosis, hepatitis, increased bilirubin [Ref ]

Hypersensitivity

Uncommon (0.1% to 1%): Aggravated allergy, allergic reactions Frequency not reported: Anaphylaxis Postmarketing reports: Hypersensitivity not otherwise specified, photosensitivity reaction [Ref ]

Immunologic

Common (1% to 10%): Influenza-like symptoms Uncommon (0.1% to 1%): Bacterial infection, herpes simplex, herpes zoster, infection, moniliasis, parasitic infection, tuberculosis [Ref ]

Musculoskeletal

Common (1% to 10%): Arthralgia, back pain, myalgia, neck/shoulder pain Uncommon (0.1% to 1%): Arthritis, arthropathy, arthrosis, bursitis, costochondritis, fibromyalgia, ischial neuralgia, jaw stiffness, leg pain, limb pain, leg cramps, lumbar disc lesion, muscle contractions, muscle cramp, muscle spasms, muscle stiffness, muscle tightness, muscle weakness, myopathy, osteoporosis, plantar fasciitis, tendinitis, tenosynovitis, tetany, twitching Postmarketing reports: Rhabdomyolysis [Ref ]

Epidemiological studies, primarily in patients aged 50 years or older, have shown an increased risk of bone fractures in patients receiving SSRIs or TCAs. [Ref ]

Ocular

Uncommon (0.1% to 1%): Abnormal accommodation, abnormal vision, blepharospasm, blurred vision, dry eyes, eye infection, eye irritation, eye pain, mydriasis, ocular hemorrhage, visual disturbance, xerophthalmia Postmarketing reports: Angle closure glaucoma, diplopia [Ref ]

Oncologic

Uncommon (0.1% to 1%): Cyst, female breast neoplasm, ovarian cyst [Ref ]

Renal

Uncommon (0.1% to 1%): Pyelonephritis, renal calculus Postmarketing reports: Acute renal failure [Ref ]

Respiratory

Common (1% to 10%): Pharyngitis, rhinitis, sinusitis, upper respiratory tract infection, yawning Uncommon (0.1% to 1%): Asthma, bronchitis, coughing, dyspnea, epistaxis, laryngitis, nasal congestion, nasopharyngitis, pneumonia, respiratory tract infection, shortness of breath, sinus congestion, sinus headache, sleep apnea, snoring, tracheitis, throat tightness Postmarketing reports: Pulmonary embolism, pulmonary hypertension of the newborn [Ref ]

References

1. Cerner Multum, Inc. "Australian Product Information." O 0

2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

3. "Product Information. Lexapro (escitalopram)." Forest Pharmaceuticals, St. Louis, MO.

4. Davidson JR, Bose A, Wang Q "Safety and efficacy of escitalopram in the long-term treatment of generalized anxiety disorder." J Clin Psychiatry 66 (2005): 1441-6

5. Jacob S, Spinler SA "Hyponatremia associated with selective serotonin-reuptake inhibitors in older adults." Ann Pharmacother 40 (2006): 1618-22

6. Covyeou JA, Jackson CW "Hyponatremia associated with escitalopram." N Engl J Med 356 (2007): 94-5

Not all side effects for Lexapro may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here .

More about Lexapro (escitalopram)

Consumer resources

Professional resources

Related treatment guides

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill. knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs. com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

Drug Status

Cefaclor medlineplus drug information, ceclor

Cefaclor

Cefaclor is used to treat certain infections caused by bacteria, such as pneumonia and other lower respiratory tract (lung) infections; and infections of the skin, ears, throat, tonsils, and urinary tract. Cefaclor is in a class of medications called cephalosporin antibiotics. It works by stopping the growth of bacteria.

Antibiotics such as cefaclor will not work for colds, flu, or other viral infections. Using antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.

How should this medicine be used?

Cefaclor comes as a capsule, an extended-release (long-acting) tablet, and a suspension (liquid) to take by mouth. The capsule and liquid are usually taken with or without food every 8 or 12 hours. The long-acting tablet is usually taken within 1 hour of eating a meal every 12 hours (twice a day) for 7 to 10 days. Take cefaclor at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take cefaclor exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Shake the suspension well before each use to mix the medication evenly.

Swallow the long-acting tablets whole; do not split, chew, or crush them.

You should begin to feel better during the first few days of treatment with cefaclor. If your symptoms do not improve or get worse, call your doctor.

Take cefaclor until you finish the prescription, even if you feel better. If you stop taking cefaclor too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.

Other uses for this medicine

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before taking cefaclor,

tell your doctor and pharmacist if you are allergic to cefaclor, other cephalosporin antibiotics such as cefadroxil. cefazolin (Ancef, Kefzol), cefdinir. cefditoren (Spectracef), cefepime (Maxipime), cefixime (Suprax), cefotaxime (Claforan), cefotetan, cefoxitin (Mefoxin), cefpodoxime. cefprozil (Cefzil), ceftaroline (Teflaro), ceftazidime ( Fortaz, Tazicef, in Avycaz), ceftibuten (Cedax), ceftriaxone (Rocephin), cefuroxime (Ceftin, Kefurox, Zinacef), and cephalexin (Keflex); penicillin antibiotics; or any other medications. Also tell your doctor if you are allergic to any of the ingredients in cefaclor capsules, extended release tablets, or suspension. Ask your pharmacist for a list of the ingredients.

tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention either of the following: anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven), and probenecid (Probalan). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

tell your doctor if you have or have ever had any kind of allergies, gastrointestinal disease (GI; affecting the stomach or intestines), especially colitis (condition that causes swelling in the lining of the colon [large intestine]), or kidney disease.

if you are taking antacids that contain magnesium or aluminum, take them 1 hour before or 1 hour after cefaclor extended release tablets.

tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking cefaclor, call your doctor.

What special dietary instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Cefaclor may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately or get emergency medical treatment:

rash

itching, prickling, burning, or stinging feeling on the skin

hives

difficulty breathing or swallowing

wheezing

swelling of the face, throat, tongue, lips, eyes, arms or legs

lack of energy, or feeling faint

joint pain

watery or bloody stools, stomach cramps, or fever during treatment or for up to two or more months after stopping treatment

a return of fever, sore throat, chills, or other signs of infection

Cefaclor may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www. fda. gov/Safety/MedWatch ) or by phone (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store the capsules and tablets at room temperature and away from excess heat and moisture (not in the bathroom). The tablets should also be stored away from light. Keep liquid medicine in the refrigerator, tightly closed, and dispose of any unused medication after 14 days.

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo. gl/c4Rm4p ) for more information if you do not have access to a take-back program.

In case of emergency/overdose

Coumadin (warfarin) uses, dosage, side effects, arefarin

Coumadin

What is Coumadin?

Coumadin (warfarin) is an anticoagulant (blood thinner). Warfarin reduces the formation of blood clots.

Coumadin is used to treat or prevent blood clots in veins or arteries, which can reduce the risk of stroke. heart attack. or other serious conditions.

Coumadin may also be used for purposes not listed in this medication guide.

Important information

You should not take Coumadin if you have a bleeding disorder, blood in your urine or stools, stomach bleeding, an infection of the lining of your heart, bleeding in your brain, recent or upcoming surgery, or if you need a spinal tap or epidural. Do not take warfarin if you cannot take it on time every day.

Do not use Coumadin if you are pregnant, unless your doctor tells you to.

Coumadin increases your risk of bleeding, which can be severe or life-threatening. You will need frequent tests to measure your blood-clotting time. Call your doctor or seek emergency medical attention if you have bleeding that will not stop, if you have blood in your urine, black or bloody stools, or if you cough up blood or vomit that looks like coffee grounds.

Many drugs can cause serious medical problems when used with warfarin. Tell your doctor about all medicines you have recently used.

Before taking this medicine

You should not take Coumadin if you are allergic to warfarin, or if you have:

hemophilia or any bleeding disorder that is inherited or caused by disease;

a blood cell disorder (such as low red blood cells or low platelets);

blood in your urine or stools, or if you have been coughing up blood;

an infection of the lining of your heart (bacterial endocarditis);

stomach or intestinal bleeding or ulcer;

very high blood pressure;

recent or upcoming surgery on your brain, spine, or eye;

recent head injury, aneurysm, or bleeding in the brain; or

if you undergo a spinal tap or spinal anesthesia (epidural).

You should not take Coumadin if you cannot be reliable in taking it because of alcoholism, psychiatric problems, dementia, or similar conditions.

Coumadin can make you bleed more easily, especially if you have:

a history of bleeding problems;

high blood pressure or severe heart disease;

kidney or liver disease;

a disease affecting the blood vessels in your brain;

a history of stomach or intestinal bleeding;

a surgery or medical emergency, or if you receive any type of injection (shot); or

if you are 65 or older; or

if you are severely ill or debilitated.

Do not use Coumadin if you are pregnant, unless your doctor tells you to. Warfarin can cause birth defects, but preventing blood clots may outweigh any risks to the baby. You may be able to take Coumadin during pregnancy if you have a mechanical heart valve. Use effective birth control to prevent pregnancy while using this medicine and for at least 1 month after your last dose. Tell your doctor right away if you become pregnant.

To make sure Coumadin is safe for you, tell your doctor if you have:

celiac sprue (an intestinal disorder);

congestive heart failure;

a connective tissue disorder such as Marfan Syndrome, Sjogren syndrome, scleroderma, rheumatoid arthritis, or lupus;

a hereditary clotting deficiency (warfarin may make your symptoms worse at first);

if you use a catheter; or

if you have ever had low blood platelets after receiving heparin.

It is not known whether warfarin passes into breast milk. Tell your doctor if you are breast-feeding a baby. Watch for signs of bruising or bleeding in the baby if you take Coumadin while you are nursing.

How should I take Coumadin?

Take Coumadin exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take Coumadin in larger or smaller amounts or for longer than your doctor tells you to.

Take Coumadin at the same time every day, with or without food. Never take a double dose of this medicine.

While using warfarin, you will need frequent "INR" or prothrombin time tests (to measure how long it takes your blood to clot). Your blood work will help your doctor determine the best dose for you. You must remain under the care of a doctor while using Coumadin.

If you have received warfarin in a hospital, call or visit your doctor 3 to 7 days after you leave the hospital. Your INR will need to be tested at that time. Do not miss any follow-up appointments.

Tell your doctor if you are sick with diarrhea, fever, chills, or flu symptoms, or if your body weight changes.

You may need to stop taking Coumadin 5 to 7 days before having any surgery or dental work. Call your doctor for instructions. You may also need to stop taking Coumadin if you need to take antibiotics, or if you have a spinal tap or spinal anesthesia (epidural).

Wear a medical alert tag or carry an ID card stating that you take warfarin. Any medical care provider who treats you should know that you are using this medicine.

Store at room temperature away from heat, moisture, and light.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can cause excessive bleeding.

What should I avoid while taking Coumadin?

Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth. You may still bleed more easily for several days after you stop taking Coumadin.

Avoid drinking alcohol.

Grapefruit juice, cranberry juice, noni juice, and pomegranate juice may interact with warfarin and lead to unwanted side effects. Avoid the use of these juice products while taking Coumadin.

Avoid making any changes in your diet without first talking to your doctor. Foods that are high in vitamin K (liver, leafy green vegetables, or vegetable oils) can make warfarin less effective. If these foods are part of your diet, eat a consistent amount on a weekly basis.

Ask your doctor before taking any medicine for pain, arthritis, fever, or swelling. This includes acetaminophen (Tylenol), aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib (Celebrex), diclofenac, indomethacin, meloxicam, and others. These medicines may affect blood clotting and may also increase your risk of stomach bleeding.

Coumadin side effects

Get emergency medical help if you have signs of an allergic reaction to Coumadin . hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Coumadin may cause you to bleed more easily, which can be severe or life-threatening. Seek emergency medical attention if you have any unusual bleeding, or bleeding that will not stop. You may also have bleeding on the inside of your body, such as in your stomach or intestines. Call your doctor at once if you have blood in your urine, black or bloody stools, or if you cough up blood or vomit that looks like coffee grounds.

Also call your doctor at once if you have:

pain, swelling, hot or cold feeling, skin changes, or discoloration anywhere on your body;

sudden and severe leg or foot pain, foot ulcer, purple toes or fingers;

sudden headache, dizziness, or weakness;

easy bruising or bleeding (nosebleeds, bleeding gums), purple or red pinpoint spots under your skin;

bleeding from wounds or needle injections that will not stop;

pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating;

dark urine, jaundice (yellowing of the skin or eyes);

little or no urinating;

numbness or muscle weakness; or

pain in your stomach, back, or sides.

Common Coumadin side effects may include:

nausea, vomiting, mild stomach pain;

bloating, gas; or

altered sense of taste.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Coumadin?

Many drugs (including some over-the-counter medicines and herbal products) can affect your INR and may increase the risk of bleeding if you take them with Coumadin. Not all possible drug interactions are listed in this medication guide. It is very important to ask your doctor and pharmacist before you start or stop using any other medicine, especially:

other medicines to prevent blood clots;

medicine to treat any type of infection, including tuberculosis;

supplements that contain vitamin K; or

an antidepressant - citalopram, duloxetine, fluoxetine, fluvoxamine, paroxetine, sertraline, venlafaxine, vilazodone, and others; seizure medicine - carbamazepine, phenobarbital, phenytoin; herbal (botanical) products - coenzyme Q10, cranberry, echinacea, garlic, ginkgo biloba, ginseng, goldenseal, or St. John's wort.

This list is not complete and many other drugs can interact with warfarin. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.

More about Coumadin (warfarin)

Consumer resources

Professional resources

Related treatment guides

Where can I get more information?

Your pharmacist can provide more information about Coumadin.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Coumadin only for the indication prescribed.

Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2016 Cerner Multum, Inc. Version: 20.01. Revision Date: 2016-06-21, 8:27:20 AM.

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Ciprofat, ciprofat

Ciplox is used to treat different types of bacterial infections. It may also be used to prevent or slow anthrax after exposure.

Take Cipro exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Take Cipro with a full glass of water (8 ounces). Drink several extra glasses of fluid each day while you are taking this medicine. Cipro may be taken with or without food, but take it at the same time each day. Shake the oral suspension (liquid) for at least 15 seconds just before you measure a dose. To be sure you get the correct dose, measure the liquid with a marked measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

When taking the Cipro oral liquid, swallow it without chewing the medicine beads you may notice in the liquid.

Do not crush, chew, or break an extended-release tablet. Swallow it whole. Breaking the pill may cause too much of the drug to be released at one time. Do not take Cipro with dairy products such as milk or yogurt, or with calcium-fortified juice. You may eat or drink these products as part of a regular meal, but do not use them alone when taking Cipro. They could make the medication less effective.

Take Cipro for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Cipro will not treat a viral infection such as the common cold or flu.

Store Cipro at room temperature away from moisture and heat. Do not allow the liquid medicine to freeze.

If you missed a dose - take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

Take exactly as prescribed by your Health Provider.

Store this medicine at room temperature away from moisture and heat. Do not allow the liquid medicine to freeze.

You should not use Ciplox if you are taking tizanidine (Zanaflex), if you have a history of myasthenia gravis, or if you are allergic to ciprofloxacin or similar antibiotics such as gemifloxacin (Factive), levofloxacin (Levaquin), moxifloxacin (Avelox), norfloxacin (Noroxin), and others.

Before taking Ciplox, tell your doctor if you have a heart rhythm disorder, kidney or liver disease, joint problems, diabetes, muscle weakness or trouble breathing, a condition called pseudotumor cerebri, a history of seizures, a history of head injury or brain tumor, low levels of potassium in your blood, a personal or family history of Long QT syndrome, or if you have ever had an allergic reaction to an antibiotic.

Do not take Ciplox with dairy products such as milk or yogurt, or with calcium-fortified juice. Avoid taking antacids, vitamin or mineral supplements, sucralfate (Carafate), or didanosine (Videx) powder or chewable tablets within 6 hours before or 2 hours after you take Ciplox. Ciprofloxacin may cause swelling or tearing of a tendon (the fiber that connects bones to muscles in the body), especially in the Achilles' tendon of the heel. Stop taking Ciplox and call your doctor at once if you have sudden pain, swelling, tenderness, stiffness, or movement problems in any of your joints. Rest the joint until you receive medical care or instructions.

You should NOT take Ciplox if:

you are also taking tizanidine (Zanaflex);

you have a history of myasthenia gravis; or

you are allergic to ciprofloxacin or similar medications such as gemifloxacin (Factive), levofloxacin (Levaquin), moxifloxacin (Avelox), ofloxacin (Floxin), norfloxacin (Noroxin), and others.

To make sure you can safely take Ciplox, tell your doctor if you have any of these other conditions:

heart rhythm disorder, especially if you take quinidine (Quin-G), disopyramide (Norpace), bretylium (Bretylol), procainamide (Pronestyl, Procan SR), amiodarone (Cordarone, Pacerone), or sotalol (Betapace);

a history of head injury or brain tumor;

a condition called pseudotumor cerebri (high pressure inside the skull that may cause headaches, vision loss, or other symptoms);

a history of allergic reaction to an antibiotic;

joint problems;

kidney or liver disease;

epilepsy or seizures;

diabetes;

muscle weakness or trouble breathing;

low levels of potassium in your blood (hypokalemia); or

a personal or family history of Long QT syndrome.

FDA pregnancy category C. It is not known whether Ciplox will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using it. Ciprofloxacin passes into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Ciplox may cause swelling or tearing of a tendon (the fiber that connects bones to muscles in the body), especially in the Achilles' tendon of the heel. These effects may be more likely to occur if you are over 60, if you take steroid medication, or if you have had a kidney, heart, or lung transplant. Stop taking Ciplox and call your doctor at once if you have sudden pain, swelling, tenderness, stiffness, or movement problems in any of your joints. Rest the joint until you receive medical care or instructions. Do not share Ciplox with another person (especially a child), even if they have the same symptoms you have.

Get emergency medical help if you have any of these signs of an allergic reaction to Ciplox: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using Ciplox and call your doctor at once if you have a serious side effect such as:

severe dizziness, fainting, fast or pounding heartbeats;

sudden pain, snapping or popping sound, bruising, swelling, tenderness, stiffness, or loss of movement in any of your joints;

diarrhea that is watery or bloody;

confusion, hallucinations, depression, unusual thoughts or behavior;

seizure (convulsions);

severe headache, ringing in your ears, dizziness, nausea, vision problems, pain behind your eyes;

pale or yellowed skin, dark colored urine, fever, weakness;

urinating less than usual or not at all;

easy bruising or bleeding;

numbness, tingling, or unusual pain anywhere in your body;

the first sign of any skin rash, no matter how mild; or

severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Less serious side effects:

nausea, vomiting;

dizziness or drowsiness;

blurred vision;

feeling nervous, anxious, or agitated; or

sleep problems (insomnia or nightmares).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

Ciplox is used to treat different types of bacterial infections. It may also be used to prevent or slow anthrax after exposure.

Take Cipro exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Take Cipro with a full glass of water (8 ounces). Drink several extra glasses of fluid each day while you are taking this medicine. Cipro may be taken with or without food, but take it at the same time each day. Shake the oral suspension (liquid) for at least 15 seconds just before you measure a dose. To be sure you get the correct dose, measure the liquid with a marked measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

When taking the Cipro oral liquid, swallow it without chewing the medicine beads you may notice in the liquid.

Do not crush, chew, or break an extended-release tablet. Swallow it whole. Breaking the pill may cause too much of the drug to be released at one time. Do not take Cipro with dairy products such as milk or yogurt, or with calcium-fortified juice. You may eat or drink these products as part of a regular meal, but do not use them alone when taking Cipro. They could make the medication less effective.

Take Cipro for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Cipro will not treat a viral infection such as the common cold or flu.

Store Cipro at room temperature away from moisture and heat. Do not allow the liquid medicine to freeze.

If you missed a dose - take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

Take exactly as prescribed by your Health Provider.

Store this medicine at room temperature away from moisture and heat. Do not allow the liquid medicine to freeze.

You should not use Ciplox if you are taking tizanidine (Zanaflex), if you have a history of myasthenia gravis, or if you are allergic to ciprofloxacin or similar antibiotics such as gemifloxacin (Factive), levofloxacin (Levaquin), moxifloxacin (Avelox), norfloxacin (Noroxin), and others.

Before taking Ciplox, tell your doctor if you have a heart rhythm disorder, kidney or liver disease, joint problems, diabetes, muscle weakness or trouble breathing, a condition called pseudotumor cerebri, a history of seizures, a history of head injury or brain tumor, low levels of potassium in your blood, a personal or family history of Long QT syndrome, or if you have ever had an allergic reaction to an antibiotic.

Do not take Ciplox with dairy products such as milk or yogurt, or with calcium-fortified juice. Avoid taking antacids, vitamin or mineral supplements, sucralfate (Carafate), or didanosine (Videx) powder or chewable tablets within 6 hours before or 2 hours after you take Ciplox. Ciprofloxacin may cause swelling or tearing of a tendon (the fiber that connects bones to muscles in the body), especially in the Achilles' tendon of the heel. Stop taking Ciplox and call your doctor at once if you have sudden pain, swelling, tenderness, stiffness, or movement problems in any of your joints. Rest the joint until you receive medical care or instructions.

You should NOT take Ciplox if:

you are also taking tizanidine (Zanaflex);

you have a history of myasthenia gravis; or

you are allergic to ciprofloxacin or similar medications such as gemifloxacin (Factive), levofloxacin (Levaquin), moxifloxacin (Avelox), ofloxacin (Floxin), norfloxacin (Noroxin), and others.

To make sure you can safely take Ciplox, tell your doctor if you have any of these other conditions:

heart rhythm disorder, especially if you take quinidine (Quin-G), disopyramide (Norpace), bretylium (Bretylol), procainamide (Pronestyl, Procan SR), amiodarone (Cordarone, Pacerone), or sotalol (Betapace);

a history of head injury or brain tumor;

a condition called pseudotumor cerebri (high pressure inside the skull that may cause headaches, vision loss, or other symptoms);

a history of allergic reaction to an antibiotic;

joint problems;

kidney or liver disease;

epilepsy or seizures;

diabetes;

muscle weakness or trouble breathing;

low levels of potassium in your blood (hypokalemia); or

a personal or family history of Long QT syndrome.

FDA pregnancy category C. It is not known whether Ciplox will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using it. Ciprofloxacin passes into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Ciplox may cause swelling or tearing of a tendon (the fiber that connects bones to muscles in the body), especially in the Achilles' tendon of the heel. These effects may be more likely to occur if you are over 60, if you take steroid medication, or if you have had a kidney, heart, or lung transplant. Stop taking Ciplox and call your doctor at once if you have sudden pain, swelling, tenderness, stiffness, or movement problems in any of your joints. Rest the joint until you receive medical care or instructions. Do not share Ciplox with another person (especially a child), even if they have the same symptoms you have.

Get emergency medical help if you have any of these signs of an allergic reaction to Ciplox: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using Ciplox and call your doctor at once if you have a serious side effect such as:

severe dizziness, fainting, fast or pounding heartbeats;

sudden pain, snapping or popping sound, bruising, swelling, tenderness, stiffness, or loss of movement in any of your joints;

diarrhea that is watery or bloody;

confusion, hallucinations, depression, unusual thoughts or behavior;

seizure (convulsions);

severe headache, ringing in your ears, dizziness, nausea, vision problems, pain behind your eyes;

pale or yellowed skin, dark colored urine, fever, weakness;

urinating less than usual or not at all;

easy bruising or bleeding;

numbness, tingling, or unusual pain anywhere in your body;

the first sign of any skin rash, no matter how mild; or

severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Less serious side effects:

nausea, vomiting;

dizziness or drowsiness;

blurred vision;

feeling nervous, anxious, or agitated; or

sleep problems (insomnia or nightmares).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

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