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Arthaxan General Information

Arthaxan - Pharmacology:

The parent compound is a prodrug, which undergoes hepatic biotransformation to the active component, 6-methoxy-2-naphthylacetic acid (6MNA), that is a potent inhibitor of prostaglandin synthesis, most likely through binding to the COX-1 and COX-2 receptors.

Arthaxan for patients

Arthaxan is a non-steroidal anti-inflammatory (NSAID) medication used to relieve pain, treat fever, and decrease inflammation and swelling. It is used commonly to treat osteoarthritis and rheumatoid arthritis. This medication should not be used by those with aspirin allergies producing symptoms of difficult breathing, red itching skin. This class of medications has been associated with ulcer and bleeding in the stomach. This is often relieved by taking the medication with food. Water retention may also occur and you should report any swelling of the feet or difficulty breathing to your physician immediately. This medication can be taken with or without food, however, food often alleviates stomach irritation.

This description is suitable for active ingredient Nabumetone

Arthaxan Interactions

In vitro studies have shown that, because of its affinity for protein, 6MNA may displace other protein-bound drugs from their binding site. Caution should be exercised when administering nabumetone with warfarin since interactions have been seen with other NSAIDs.

Concomitant administration of an aluminum-containing antacid had no significant effect in the bioavailability of 6MNA. When administered with food or milk, there is more rapid absorption; however, the total amount of 6MNA in the plasma is unchanged .

Arthaxan Contraindications

Arthaxan is contraindicated in patients who have previously exhibited hypersensitivity to it.

Arthaxan is contraindicated in patients in whom nabumetone, aspirin or other NSAIDs induce asthma, urticaria or other allergic-type reactions. Fatal asthmatic reactions have been reported in such patients receiving NSAIDs.

This description is suitable for active ingredient Nabumetone

Arthaxan tags categories:

Arthaxan General Information

Arthaxan - Pharmacology:

The parent compound is a prodrug, which undergoes hepatic biotransformation to the active component, 6-methoxy-2-naphthylacetic acid (6MNA), that is a potent inhibitor of prostaglandin synthesis, most likely through binding to the COX-1 and COX-2 receptors.

Arthaxan for patients

Arthaxan is a non-steroidal anti-inflammatory (NSAID) medication used to relieve pain, treat fever, and decrease inflammation and swelling. It is used commonly to treat osteoarthritis and rheumatoid arthritis. This medication should not be used by those with aspirin allergies producing symptoms of difficult breathing, red itching skin. This class of medications has been associated with ulcer and bleeding in the stomach. This is often relieved by taking the medication with food. Water retention may also occur and you should report any swelling of the feet or difficulty breathing to your physician immediately. This medication can be taken with or without food, however, food often alleviates stomach irritation.

This description is suitable for active ingredient Nabumetone

Arthaxan Interactions

In vitro studies have shown that, because of its affinity for protein, 6MNA may displace other protein-bound drugs from their binding site. Caution should be exercised when administering nabumetone with warfarin since interactions have been seen with other NSAIDs.

Concomitant administration of an aluminum-containing antacid had no significant effect in the bioavailability of 6MNA. When administered with food or milk, there is more rapid absorption; however, the total amount of 6MNA in the plasma is unchanged .

Arthaxan Contraindications

Arthaxan is contraindicated in patients who have previously exhibited hypersensitivity to it.

Arthaxan is contraindicated in patients in whom nabumetone, aspirin or other NSAIDs induce asthma, urticaria or other allergic-type reactions. Fatal asthmatic reactions have been reported in such patients receiving NSAIDs.

This description is suitable for active ingredient Nabumetone

Arthaxan tags categories: